TRANSMEMBRANE HELICES ARE AN OVER-PRESENTED AND EVOLUTIONARILY CONSERVED SOURCE OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I AND II EPITOPES

Transmembrane Helices Are an Over-Presented and Evolutionarily Conserved Source of Major Histocompatibility Complex Class I and II Epitopes

Cytolytic T cell responses are predicted to be biased towards membrane proteins.The peptide-binding grooves of most alleles of histocompatibility complex class 49ers gold hex code I (MHC-I) are relatively hydrophobic, therefore peptide fragments derived from human transmembrane helices (TMHs) are predicted to be presented more often as would be exp

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Unveiling the relationship between social anxiety, loneliness, motivations, and problematic smartphone use: A network approach

Background: Previous studies suggested social anxiety as an essential risk factor for problematic smartphone use, but the complex interactions and the most influential components affecting this relationship remain unclear.This study capitalizes on network analysis to identify the central factors and possible mediating paths among social anxiety, lo

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Comamonas testosteroni: Is It Still a Rare Human Pathogen

Comamonas testosteroni (formally Pseudomonas testosteroni) is common environmental bacterium that is not part of the human microbiome.Since hanes 42tb its identification as a human pathogen in 1987, numerous reports have drizzled in, implicating this organism for various infections.Although these organisms are of low virulence, some of their obscur

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